Item Type | Name |
Concept
|
Chromosomes, Human, Pair 6
|
Concept
|
Developmental Disabilities
|
Concept
|
Chromosomes, Human, Pair 22
|
Concept
|
Chromosomes, Human, Pair 5
|
Concept
|
Chromosomes, Human, Pair 7
|
Concept
|
Leukemia, Erythroblastic, Acute
|
Concept
|
Leukemia
|
Concept
|
Chromosomes, Human, Pair 9
|
Concept
|
Models, Molecular
|
Concept
|
Mice, Transgenic
|
Concept
|
Mammary Tumor Virus, Mouse
|
Concept
|
Mice, Inbred BALB C
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Mice, Nude
|
Concept
|
Humans
|
Concept
|
Leukemia, Mast-Cell
|
Concept
|
Leukemia, Radiation-Induced
|
Concept
|
Leukemia, Lymphocytic, Chronic, B-Cell
|
Concept
|
Leukemia, Myeloid
|
Concept
|
Proportional Hazards Models
|
Concept
|
Models, Animal
|
Concept
|
Leukemia, Myeloid, Acute
|
Concept
|
Mice, Knockout
|
Concept
|
Gene Expression Regulation, Developmental
|
Concept
|
Chromosomes, Artificial, Human
|
Concept
|
Mice
|
Concept
|
Leukemia, Promyelocytic, Acute
|
Concept
|
Leukemia, Myelomonocytic, Chronic
|
Concept
|
Genome, Human
|
Concept
|
Precursor Cell Lymphoblastic Leukemia-Lymphoma
|
Concept
|
Myeloid-Lymphoid Leukemia Protein
|
Concept
|
Disease Models, Animal
|
Concept
|
Mice, Mutant Strains
|
Concept
|
Models, Biological
|
Concept
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive
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Concept
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Chromosomes, Human, X
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Academic Article
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The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model.
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Academic Article
|
TTID: A novel gene at 5q31 encoding a protein with titin-like features.
|
Academic Article
|
Molecular characterization of KLHL3, a human homologue of the Drosophila kelch gene.
|
Academic Article
|
cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins.
|
Academic Article
|
Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.
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Academic Article
|
Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q).
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Academic Article
|
Pre-transplant ganciclovir and post transplant high-dose valacyclovir reduce CMV infections after alemtuzumab-based conditioning.
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Academic Article
|
Successful autologous stem cell collection in patients with chronic myeloid leukemia in complete cytogenetic response, with quantitative measurement of BCR-ABL expression in blood, marrow, and apheresis products.
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Academic Article
|
Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins.
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Academic Article
|
A phase I biological study of MG98, an oligodeoxynucleotide antisense to DNA methyltransferase 1, in patients with high-risk myelodysplasia and acute myeloid leukemia.
|
Academic Article
|
Outcomes of patients with AML and MDS who relapse or progress after reduced intensity allogeneic hematopoietic cell transplantation.
|
Academic Article
|
Therapy-related myeloid leukemia.
|
Academic Article
|
Deletion of the der(9q) in chronic myeloid leukemia: the controversy continues.
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Academic Article
|
High levels of tRNA abundance and alteration of tRNA charging by bortezomib in multiple myeloma.
|
Academic Article
|
Allogeneic stem cell transplantation with alemtuzumab-based conditioning for patients with advanced chronic myelogenous leukemia.
|
Academic Article
|
Performance status and comorbidity predict transplant-related mortality after allogeneic hematopoietic cell transplantation.
|
Academic Article
|
The next frontier for stem cell transplantation: finding a donor for all.
|
Academic Article
|
The impact of MYC expression in lymphoma biology: beyond Burkitt lymphoma.
|
Academic Article
|
Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines.
|
Academic Article
|
Phase I study of dose-escalated busulfan with fludarabine and alemtuzumab as conditioning for allogeneic hematopoietic stem cell transplant: reduced clearance at high doses and occurrence of late sinusoidal obstruction syndrome/veno-occlusive disease.
|
Academic Article
|
Patterns and kinetics of T-cell chimerism after allo transplant with alemtuzumab-based conditioning: mixed chimerism protects from GVHD, but does not portend disease recurrence.
|
Academic Article
|
Treatment of therapy-related myeloid neoplasms with high-dose cytarabine/mitoxantrone followed by hematopoietic stem cell transplant.
|
Academic Article
|
Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse.
|
Academic Article
|
Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage.
|
Academic Article
|
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
|
Academic Article
|
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
|
Academic Article
|
Aberrant RNA splicing and its functional consequences in cancer cells.
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Academic Article
|
The use of hypomethylating agents in the treatment of hematologic malignancies.
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Academic Article
|
Successful allogeneic transplantation of patients with suspected prior invasive mold infection.
|
Academic Article
|
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.
|
Academic Article
|
High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).
|
Academic Article
|
Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions.
|
Academic Article
|
Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
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Academic Article
|
Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors.
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Academic Article
|
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.
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Academic Article
|
A drug that stops traffic at the nuclear border.
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Academic Article
|
Phase I-II study of clofarabine-melphalan-alemtuzumab conditioning for allogeneic hematopoietic cell transplantation.
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Academic Article
|
Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer.
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Academic Article
|
The histone code and treatments for acute myeloid leukemia.
|
Academic Article
|
Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma.
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Academic Article
|
Molecular biology. Preference by exclusion.
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Academic Article
|
Pretreatment C-reactive protein is a predictor for outcomes after reduced-intensity allogeneic hematopoietic cell transplantation.
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Academic Article
|
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
|
Academic Article
|
Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia.
|
Academic Article
|
An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.
|
Academic Article
|
Dnmt3a is essential for hematopoietic stem cell differentiation.
|
Academic Article
|
Identification and molecular characterization of a novel 3′ mutation in RUNX1 in a family with familial platelet disorder.
|
Academic Article
|
HMGA2 levels in CML: reflective of miRNA gene regulation in a hematopoietic tumor?
|
Academic Article
|
Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial.
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Academic Article
|
Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation.
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Academic Article
|
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
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Academic Article
|
Profiles in leukemia.
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Academic Article
|
Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys.
|
Academic Article
|
Fludarabine, melphalan, and alemtuzumab conditioning in adults with standard-risk advanced acute myeloid leukemia and myelodysplastic syndrome.
|
Academic Article
|
A phase I and pharmacokinetic study of XK469R (NSC 698215), a quinoxaline phenoxypropionic acid derivative, in patients with refractory acute leukemia.
|
Academic Article
|
Implications of FLT3 mutations in the therapy of acute myeloid leukemia.
|
Academic Article
|
The identification and characterisation of novel KIT transcripts in aggressive mast cell malignancies and normal CD34+ cells.
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Academic Article
|
DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
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Academic Article
|
Getting to the root of the stem cell in mutated chronic myeloid leukemia.
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Academic Article
|
T-cell-depleted allogeneic transplant without donor leukocyte infusions results in excellent long-term survival in patients with multiply relapsed Lymphoma. Predictors for survival after transplant relapse.
|
Academic Article
|
Influence of related donor age on outcomes after peripheral blood stem cell transplantation.
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Academic Article
|
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis.
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Academic Article
|
Introduction of intersubunit disulfide bonds in the membrane-distal region of the influenza hemagglutinin abolishes membrane fusion activity.
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Academic Article
|
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability.
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Academic Article
|
Defining the steps in a multistep mouse model for mammary carcinogenesis.
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Academic Article
|
Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis.
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Academic Article
|
Identifying familial myelodysplastic/acute leukemia predisposition syndromes through hematopoietic stem cell transplantation donors with thrombocytopenia.
|
Academic Article
|
High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis.
|
Academic Article
|
Genome-wide variation of cytosine modifications between European and African populations and the implications for complex traits.
|
Academic Article
|
2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine levels.
|
Academic Article
|
Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.
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Academic Article
|
Proposal for the clinical detection and management of patients and their family members with familial myelodysplastic syndrome/acute leukemia predisposition syndromes.
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Academic Article
|
Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells.
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Academic Article
|
Immune reconstitution after combined haploidentical and umbilical cord blood transplant.
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Academic Article
|
Perturbations of 5-hydroxymethylcytosine patterning in hematologic malignancies.
|
Academic Article
|
Randomized open-label phase II study of decitabine in patients with low- or intermediate-risk myelodysplastic syndromes.
|
Academic Article
|
Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
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Academic Article
|
TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
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Academic Article
|
Cell characterization using a protein-functionalized pore.
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Academic Article
|
Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.
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Academic Article
|
A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.
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Academic Article
|
Hematopoietic stem-cell transplantation for advanced systemic mastocytosis.
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Academic Article
|
Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma.
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Academic Article
|
New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine.
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Academic Article
|
Node-pore sensing enables label-free surface-marker profiling of single cells.
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Academic Article
|
Inherited predisposition to acute myeloid leukemia.
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Academic Article
|
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
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Academic Article
|
Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.
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Academic Article
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Recognizing familial myeloid leukemia in adults.
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Academic Article
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Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy.
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Academic Article
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A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia.
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Academic Article
|
Alterations of 5-hydroxymethylcytosine in human cancers.
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Academic Article
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Large conserved domains of low DNA methylation maintained by Dnmt3a.
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Academic Article
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DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.
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Academic Article
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The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
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Academic Article
|
Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes.
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Academic Article
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A new family with a germline ANKRD26 mutation and predisposition to myeloid malignancies.
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Academic Article
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Familial myelodysplastic syndrome/acute leukemia syndromes: a review and utility for translational investigations.
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Academic Article
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On the origin of leukemic species.
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Academic Article
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Geriatric assessment to predict survival in older allogeneic hematopoietic cell transplantation recipients.
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Academic Article
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The mechanistic role of DNA methylation in myeloid leukemogenesis.
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Academic Article
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Linking the genetic architecture of cytosine modifications with human complex traits.
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Academic Article
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TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.
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Academic Article
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5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy.
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Academic Article
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Characterization of CpG sites that escape methylation on the inactive human X-chromosome.
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Academic Article
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DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.
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Academic Article
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Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia.
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Academic Article
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TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer.
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Academic Article
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Correspondence Regarding the Consensus Statement from the Worldwide Network for Blood and Marrow Transplantation Standing Committee on Donor Issues.
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Academic Article
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Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia.
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Academic Article
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Epigenetic Control of Apolipoprotein E Expression Mediates Gender-Specific Hematopoietic Regulation.
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Academic Article
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Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice.
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Academic Article
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Increased DNA methylation of Dnmt3b targets impairs leukemogenesis.
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Academic Article
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Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies.
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Academic Article
|
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.
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Academic Article
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Reduced intensity haplo plus single cord transplant compared to double cord transplant: improved engraftment and graft-versus-host disease-free, relapse-free survival.
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Academic Article
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Frequency and Risk Factors Associated with Cord Graft Failure after Transplant with Single-Unit Umbilical Cord Cells Supplemented by Haploidentical Cells with Reduced-Intensity Conditioning.
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Academic Article
|
Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled, phase 3 trial.
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Academic Article
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Evaluation of Patients and Families With Concern for Predispositions to Hematologic Malignancies Within the Hereditary Hematologic Malignancy Clinic (HHMC).
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Academic Article
|
Incidence and predictors of respiratory viral infections by multiplex PCR in allogeneic hematopoietic cell transplant recipients 50 years and older including geriatric assessment.
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Academic Article
|
Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients.
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Academic Article
|
Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes.
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Academic Article
|
Identifying Inherited and Acquired Genetic Factors Involved in Poor Stem Cell Mobilization and Donor-Derived Malignancy.
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Academic Article
|
Genetic predisposition to leukemia and other hematologic malignancies.
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Academic Article
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How I diagnose and manage individuals at risk for inherited myeloid malignancies.
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Academic Article
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Efficacy of single-agent decitabine in relapsed and refractory acute myeloid leukemia.
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Academic Article
|
Germline ETV6 mutations and predisposition to hematological malignancies.
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Academic Article
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Genetic predisposition to hematologic malignancies: management and surveillance.
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Academic Article
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Recognition of familial myeloid neoplasia in adults.
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Academic Article
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Therapy-related myeloid neoplasms: when genetics and environment collide.
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Academic Article
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Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
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Academic Article
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Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies.
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Academic Article
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Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma.
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Academic Article
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Hereditary Myelodysplastic Syndrome and Acute Myeloid Leukemia: Diagnosis, Questions, and Controversies.
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Academic Article
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Treatment of Acute Promyelocytic Leukemia in Adults.
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Academic Article
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MBD4: guardian of the epigenetic galaxy.
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Academic Article
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Reduced-Intensity Allogeneic Transplant for Acute Myeloid Leukemia and Myelodysplastic Syndrome Using Combined CD34-Selected Haploidentical Graft and a Single Umbilical Cord Unit Compared with Matched Unrelated Donor Stem Cells in Older Adults.
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Academic Article
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Identifying patients with genetic predisposition to acute myeloid leukemia.
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Academic Article
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A phase I study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia.
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Academic Article
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Mutant RUNX1 and histone tales.
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Academic Article
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Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways.
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Academic Article
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Characterization of cancer comorbidity prior to allogeneic hematopoietic cell transplantation.
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Academic Article
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Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes.
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Academic Article
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Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.
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Academic Article
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Somatic mutation panels: Time to clear their names.
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Academic Article
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FouNdER mutations confer risk for leukemias.
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Academic Article
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Inherited predisposition to myeloid malignancies.
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Academic Article
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Correct application of variant classification guidelines in germline RUNX1 mutated disorders to assist clinical diagnosis.
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Academic Article
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ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants.
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Academic Article
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5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma.
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Academic Article
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A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia.
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Academic Article
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MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome.
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Academic Article
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How I curate: applying American Society of Hematology-Clinical Genome Resource Myeloid Malignancy Variant Curation Expert Panel rules for RUNX1 variant curation for germline predisposition to myeloid malignancies.
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Academic Article
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RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.
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Academic Article
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Breaking the spatial constraint between neighboring zinc fingers: a new germline mutation in GATA2 deficiency syndrome.
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Academic Article
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Inherited Thrombocytopenia Caused by Germline ANKRD26 Mutation Should Be Considered in Young Patients With Suspected Myelodysplastic Syndrome.
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Academic Article
|
HIF-1 directly induces TET3 expression to enhance 5-hmC density and induce erythroid gene expression in hypoxia.
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Academic Article
|
Assessment of technical heterogeneity among diagnostic tests to detect germline risk variants for hematopoietic malignancies.
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Academic Article
|
Regulation of telomeric function by DNA methylation differs between humans and mice.
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Academic Article
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Heterozygous germ line CSF3R variants as risk alleles for development of hematologic malignancies.
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Academic Article
|
Identifying potential germline variants from sequencing hematopoietic malignancies.
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Academic Article
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Identifying potential germline variants from sequencing hematopoietic malignancies.
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Academic Article
|
Germline mutations in MDS/AML predisposition disorders.
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Academic Article
|
Germline variants drive myelodysplastic syndrome in young adults.
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Academic Article
|
Inherited predisposition to haematopoietic malignancies: overcoming barriers and exploring opportunities.
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Academic Article
|
Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer.
|
Academic Article
|
RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function.
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Academic Article
|
Study of inherited thrombocytopenia resulting from mutations in ETV6 or RUNX1 using a human pluripotent stem cell model.
|
Academic Article
|
Clinical features and survival outcomes in patients with chronic myelomonocytic leukemia arising in the context of germline predisposition syndromes.
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Academic Article
|
The RUNX1 database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy.
|
Academic Article
|
Increased burden of familial-associated early-onset cancer risk among minority Americans compared to non-Latino Whites.
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Academic Article
|
Anticipation in hematopoietic malignancies: biology, bias, or both?
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Academic Article
|
BET inhibitors enhance embryonic and fetal globin expression in erythroleukemia cell lines.
|
Academic Article
|
Therapy-related myeloid neoplasms in 109 patients after radiation monotherapy.
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Academic Article
|
Inherited Susceptibility to Hematopoietic Malignancies in the Era of Precision Oncology.
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Academic Article
|
The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
|
Academic Article
|
A practical guide to interpreting germline variants that drive hematopoietic malignancies, bone marrow failure, and chronic cytopenias.
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Academic Article
|
Feasibility and limitations of cultured skin fibroblasts for germline genetic testing in hematologic disorders.
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Academic Article
|
Clonal hematopoiesis in patients with ANKRD26 or ETV6 germline mutations.
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Academic Article
|
Germline CHEK2 and ATM Variants in Myeloid and Other Hematopoietic Malignancies.
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Academic Article
|
International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.
|
Academic Article
|
Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN.
|
Academic Article
|
Efficacy and tolerability of a modified pediatric-inspired intensive regimen for acute lymphoblastic leukemia in older adults.
|
Academic Article
|
Clinical and molecular response of acute myeloid leukemia harboring non-canonical FLT3 N676K driver mutations to contemporary FLT3 inhibitors.
|
Academic Article
|
MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia.
|
Academic Article
|
Germ line DDX41 mutations define a unique subtype of myeloid neoplasms.
|
Academic Article
|
Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones.
|
Academic Article
|
Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.
|
Academic Article
|
Germ line predisposition variants occur in myelodysplastic syndrome patients of all ages.
|
Academic Article
|
Allogeneic hematopoietic stem cell transplant outcomes in adults with inherited myeloid malignancies.
|
Academic Article
|
DDX41-associated susceptibility to myeloid neoplasms.
|
Academic Article
|
Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia.
|
Academic Article
|
Significance of hereditary gene alterations for the pathogenesis of adult bone marrow failure versus myeloid neoplasia.
|
Academic Article
|
Classification of rare pediatric myeloid neoplasia-Quo vadis?
|
Academic Article
|
Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks.
|
Academic Article
|
(R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers.
|
Grant
|
The Role of DNMT3B in the DNA Methylation of Cancer Cells
|
Grant
|
A chemical crosslinking strategy to determine DNA methylating protein complexes
|
Grant
|
Epigenetic and Genetic Dissection of Drug Response
|
Academic Article
|
Germline loss-of-function BRCA1 and BRCA2 mutations and risk of de novo hematopoietic malignancies.
|
Academic Article
|
Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.
|
Academic Article
|
Germline predisposition to clonal hematopoiesis.
|
Academic Article
|
Germ line risk variants: beyond cancer.
|
Academic Article
|
Donor-Derived Malignancy and Transplantation Morbidity: Risks of Patient and Donor Genetics in Allogeneic Hematopoietic Stem Cell Transplantation.
|
Academic Article
|
Germline predisposition traits in allogeneic hematopoietic stem-cell transplantation for myelodysplastic syndromes: a survey-based study and position paper on behalf of the Chronic Malignancies Working Party of the EBMT.
|
Academic Article
|
Sequential tumor molecular profiling identifies likely germline variants.
|
Academic Article
|
Acute lymphoblastic leukemia with myeloid mutations is a high-risk disease associated with clonal hematopoiesis.
|
Academic Article
|
Insights into the Molecular Mechanisms of Genetic Predisposition to Hematopoietic Malignancies: The Importance of Gene-Environment Interactions.
|
Academic Article
|
Germline predisposition to myeloid neoplasms: Characteristics and management of high versus variable penetrance disorders.
|